
CraniSeal® and SpineSeal™ Dural Sealants THE CLASSIC CHOICE
Achieve peace of mind and watertight closure with the CraniSeal and SpineSeal Dural Sealant Systems
Achieve peace of mind and watertight closure with the CraniSeal and SpineSeal Dural Sealant Systems
CraniSeal and SpineSeal use hydrogel technology to achieve watertight closure and reduce the risk of cerebrospinal fluid leak following sutured dural repair*
CraniSeal and SpineSeal are among the first medical devices to be approved through the FDA's Section 216 pathway.
Product Code: CS-2055
*CraniSeal is indicated for use in patients ≥ 18 years of age as an adjunct to sutured dural repair during cranial surgery to provide watertight closure.
CraniSeal has been determined by the US FDA to be identical to the DuraSeal® Dural Sealant.
† SpineSeal is indicated for use as an adjunct to sutured dural repair during spinal surgery to provide watertight closure.
SpineSeal has been determined by the US FDA to be identical to the DuraSeal Exact® Dural Sealant.
Product Code: SS-2055
The CraniSeal and SpineSeal kits include the same components that neurosurgeons are used to - ensuring rapid adoption with minimal training required
*The CraniSeal Dural Sealant is indicated for use in patients ≥ 18 years of age as an adjunct to sutured dural repair during cranial surgery to provide watertight closure. CraniSeal has been determined by the US FDA to befunctionally the same as DuraSeal® Dural Sealant. Please refer to Summary of Safety and Effectiveness Data (SSED) at www.fda.gov for CraniSeal.
† The SpineSeal Spine Sealant is indicated for use as an adjunct to sutured dural repair during spinal surgery to provide watertight closure. Please refer to Summary of Safety and Effectiveness Data (SSED) at www.fda.gov for SpineSeal. SpineSeal has been determined by the US FDA to be functionally the same as DuraSealExact®Dural Sealant.
‡ Data on file.
§ DuraSeal®is a registered trademark of Integra LifeSciencesCorporation or its subsidiaries in the United States and/or other countries.
‖ Data on File
¶ DuraSeal®Exact is a registered trademark of Integra LifeSciencesCorporation or its subsidiaries in the United States and/or other countries.
® Copyright 2025 Pramand LLC. All rights reserved.
Pramand, LLC
201 Burlington Road
Bedford, MA 01730
PRA-MKT-0003 Rev D
We use cookies to analyze website traffic and optimize your website experience. By accepting our use of cookies, your data will be aggregated with all other user data.